Xeris Biopharma (XERS) Reports Q4 Earnings: What Key Metrics Have to Say

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Xeris Biopharma (XERS) Reports Q4 Earnings: What Key Metrics Have to Say

Xeris Biopharma (XERS) reported $85.81 million in revenue for the quarter ended December 2025, representing a year-over-year increase of 42.8%. EPS of $0.06 for the same period compares to -$0.03 a year ago.

The reported revenue represents a surprise of +5.38% over the Zacks Consensus Estimate of $81.43 million. With the consensus EPS estimate being $0.03, the EPS surprise was +84.62%.

While investors closely watch year-over-year changes in headline numbers -- revenue and earnings -- and how they compare to Wall Street expectations to determine their next course of action, some key metrics always provide a better insight into a company's underlying performance.

As these metrics influence top- and bottom-line performance, comparing them to the year-ago numbers and what analysts estimated helps investors project a stock's price performance more accurately.

Here is how Xeris Biopharma performed in the just reported quarter in terms of the metrics most widely monitored and projected by Wall Street analysts: Product Revenue- Gvoke: $24.65 million compared to the $26.45 million average estimate based on three analysts. The reported number represents a change of +6% year over year. Product Revenue- Recorlev: $45.33 million compared to the $43.67 million average estimate based on three analysts. The reported number represents a change of +307.5% year over year. Revenue- Royalty, contract and other: $2.38 million versus the three-analyst average estimate of $1.02 million. The reported number represents a year-over-year change of -23.3%. Revenue- Product revenue, net: $83.43 million versus the three-analyst average estimate of $81.19 million. The reported number represents a year-over-year change of +46.4%. Product Revenue- Keveyis: $12.8 million versus the three-analyst average estimate of $11.07 million. The reported number represents a year-over-year change of -43.4%.

View all Key Company Metrics for Xeris Biopharma here>>>

Shares of Xeris Biopharma have returned -16.9% over the past month versus the Zacks S&P 500 composite's -1.3% change. The stock currently has a Zacks Rank #3 (Hold), indicating that it could perform in line with the broader market in the near term.

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This article originally published on Zacks Investment Research (zacks.com).

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