Valeur202020212022202320242025TTMFrais de vente, généraux et administratifs140 M111.13 M115.99 M158.31 M144.27 M82.26 M70.03 MRecherche et développement88.06 M70.41 M44.27 M116.08 M111.42 M95.14 M89.64 MRésultat d'exploitation142.94 M232.26 M250.34 M-945.43 M93.12 M98.5 M200.18 MTotal des produits hors exploitation-34.08 M-31.6 M2.08 M-2.64 M-27.93 M-28.48 M-28.71 MCharges d'intérêts, nettes des intérêts capitalisés29.48 M31.15 M7.6 M21.63 M33.03 M32.75 M33.82 MRésultat hors exploitation, hors charges d'intérêts-63.56 M-62.75 M-5.51 M-24.27 M-28.57 M-61.42 M-62.73 MRevenus/dépenses exceptionnels24 K———640 K193 K198 KRésultat avant impôts108.86 M200.66 M252.42 M-948.07 M65.2 M70.03 M171.47 MPart des actionnaires dans le résultat———————Impôts2.69 M-327.79 M77.36 M83.49 M64.32 M46.01 M69.29 MIntérêts ne donnant pas le contrôle / intérêts minoritaires———-29.32 M-29.32 M——Autres produits/charges après impôts———————Résultat net avant activités abandonnées143.61 M565.89 M175.06 M-1 B880 K24.02 M102.18 MActivités abandonnées-37.44 M-37.44 M—————Résultat net106.18 M528.45 M175.06 M-1 B880 K24.02 M102.18 MAjustement de dilution———————Dividendes privilégiés———————Résultat net dilué revenant aux actionnaires ordinaires106.18 M528.45 M179.51 M155.44 M880 K24.02 M102.18 MBénéfice par action de base (BPA de base)0.673.261.13-6.450.010.150.64Bénéfice par action dilué (BPA dilué)0.663.210.96-6.450.010.150.6Nombre moyen d'actions de base en circulation159.43 M162.25 M154.37 M155.44 M159.08 M161.84 M—Nombre d'actions en circulation après dilution160.66 M164.42 M186.31 M155.44 M160.08 M162.98 M—EBITDA145.24 M233.76 M251.74 M-944.23 M94.32 M99.6 M202.03 MEBIT142.94 M232.26 M250.34 M-945.43 M93.12 M98.5 M200.18 MCoût des ventes3.14 M——————Autres coûts des ventes———————Amortissements (flux de trésorerie)2.3 M1.5 M1.4 M1.2 M1.2 M1.1 M1.84 M
Ironwood Pharmaceuticals, Inc. - Class A Common Stock
Ironwood Pharmaceuticals, Inc. is a publicly traded pharmaceutical company. It was originally called Microbia, Inc.
Microbia was founded by postdocs from the lab of Gerald Fink at the Whitehead Institute to commercialize approaches that had been developed in the lab to improve industrial fermentation of fungi, to genetically engineer them to produce secondary metabolites more efficiently or to produce new ones as leads for drug discovery or as products for use in industry, and to identify drug targets in fungi for antifungal drug discovery. In 2002 the company hired John Talley to lead their antifungal drug discovery efforts, which at the time were focused on identifying small molecules that could inhibit fungal invasins, along with Mark Currie who had also worked at Searle division of Monsanto with Talley, and then had gone to Sepracor, and also Richard Bailey, who had run Monsanto's nutritional business. Currie directed the efforts that led to the discovery of linaclotide, which was based on an enterotoxin produced by some strains of Escherichia coli that cause traveler’s diarrhea.
By 2004 the company had raised $99M and was preparing a Phase I trial for linaclotide.